Every thought or action brings together different kinds of information. If we go to the fridge for milk, we combine knowledge of the spatial layout of the kitchen, sensory input from the contents of the fridge, our goal of making tea and our knowledge of what tea requires, as well as the commands that move […]
Does decoding the brain tell us about the mind?
In the past decade, scientists have been excited about new analytical methods, using machine learning, that allow us to track information coded in patterns of brain activity. We can use them to “read” out from brain activity what participants are looking at or paying attention to, or even what they are imagining. But are the […]
Memory control in trauma’s wake
After a traumatic event, people often experience intrusive thoughts about the experience. Such memories can be powerfully distressing, so survivors of trauma typically report that they try to suppress them. Fortunately, intrusive thoughts tend to decline over time. But up to now, researchers have not known how this happens: is it merely that memories of […]
Genetic diagnosis and autistic features in young people with intellectual disabilities
Around 1% of the global population has intellectual disability (ID, also known as learning disability), meaning lifelong difficulties with cognitive functions. With recent advances in genomic technologies, it is possible to find a specific cause (genetic diagnosis) for the majority of people with severe ID. But whether and how genetic diagnosis is relevant to each […]
SYT1 gene variants cause a complex disorder by slowing neurotransmission
In 2015, Kate Baker and colleagues published the first report of a child with severe, complex disabilities and a variant in a gene called Synaptotagmin 1 (SYT1). SYT1 co-ordinates communication between brain cells by triggering the release of neurotransmitter-filled vesicles. Following this discovery, genomic testing laboratories around the world began to look for similar cases. […]
Problems in imagining future positive experiences are linked with low mood after brain injury
An acquired brain injury (ABI) refers to damage to the brain as the result of an interruption to its blood supply (stroke), from a severe blow to the head (traumatic brain injury) or from a brain tumour. Many people make excellent recoveries from these injuries. However, for some, it can bring about major changes that […]
Why does brain activity increase in old age?
Increased prefrontal cortex activity during tasks such as encoding new memories is often observed in some healthy older adults, despite overall age-related declines in memory and other cognitive functions. This study compared two leading models of brain ageing: that the frontal cortex is either compensating for impairments elsewhere in the brain; or alternatively, that structural […]
Jacobs Foundation awards UCI $11 million to improve digital technologies for children
The Jacobs Foundation has awarded a five-year, nearly $11 million grant to the University of California, Irvine for the creation of a collaborative network to help tailor digital technologies for children. Connecting the EdTech Research EcoSystem (CERES) will bring together global leaders in computer science, psychology, neuroscience, education and educational technology in pursuit of this […]
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MRC Cognition and Brain Sciences Unit

