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Maris Vainre
Graduate student

Maris.Vainre@mrc-cbu.cam.ac.uk
01223 766 166
Programme Leader: Tim Dalgleish
CBSU publications
Montero-Marin, J., Hinze, V., Crane, C., Dalrymple, N., Kempnich, M.E.J., Lord, L., Slaghekke, Y., Tudor, K., Byford, S., DALGLEISH, T., Ford, T.J., Greenberg, M.T., Ukoumunne, O.C., Williams, J.M.G., Ahmed, S., Allwood, M., Ball, S., Bennett, M., Blakemore, S., Casey, T., De Wilde, K., DUNNING, D., Farley, E-R., Fletcher, K., Foulkes, L., Ganguli, P., Griffin, C., Griffiths, K., Jones, B., Kappelmann, N., Komninidou, K., Laws, S., Leung, J., Medlicott, E., Nuthall, E., PARKER, J., Phillips, A., Raja, A., Palmer, L., Petit, A., Piera Pi-Sunyer, B., Pryor-Nitsch, I., Radley, L., Sakhardande, J.A., Shackleford, J., Sonley, A., Taylor, L., Tickell, A., VAINRE, M. , Viner, R.M., Wainman, B., Warriner, L., Kuyken, W. (In Press) Do adolescents like school-based mindfulness training? Predictors of mindfulness practice and responsiveness in the MYRIAD trial, Journal of the American Academy of Child & Adolescent Psychiatry [Open Access]

Wagner, A.P., Galante, J., Dufour, G., Barton, G., Stochl, J., VAINRE, M. and Jones, P. (2023) Cost-effectiveness of providing university students with a mindfulness-based intervention to reduce psychological distress: economic evaluation of a pragmatic randomised controlled trial, Objective Increasing numbers of young people attending university has raised concerns about the capacity of student mental health services to support them. We conducted a randomised controlled trial (RCT) to explore whether provision of an 8 week mindfulness course adapted for university students (Mindfulness Skills for Students—MSS), compared with university mental health support as usual (SAU), reduced psychological distress during the examination period. Here, we conduct an economic evaluation of MSS+SAU compared with SAU. Design and setting Economic evaluation conducted alongside a pragmatic, parallel, single-blinded RCT comparing provision of MSS+SAU to SAU. Participants 616 university students randomised. Primary and secondary outcome measures The primary economic evaluation assessed the cost per quality-adjusted life year (QALY) gained from the perspective of the university counselling service. Costs relate to staff time required to deliver counselling service offerings. QALYs were derived from the Clinical Outcomes in Routine Evaluation Dimension 6 Dimension (CORE-6D) preference based tool, which uses responses to six items of the Clinical Outcomes in Routine Evaluation Outcome Measure (CORE-OM; primary clinical outcome measure). Primary follow-up duration was 5 and 7 months for the two recruitment cohorts. Results It was estimated to cost £1584 (2022 prices) to deliver an MSS course to 30 students, £52.82 per student. Both costs (adjusted mean difference: £48, 95% CI £40–£56) and QALYs (adjusted mean difference: 0.014, 95% CI 0.008 to 0.021) were significantly higher in the MSS arm compared with SAU. The incremental cost-effectiveness ratio (ICER) was £3355, with a very high (99.99%) probability of being cost-effective at a willingness-to-pay threshold of £20 000 per QALY. Conclusions MSS leads to significantly improved outcomes at a moderate additional cost. The ICER of £3355 per QALY suggests that MSS is cost-effective when compared with the UK’s National Institute for Health and Care Excellence thresholds of £20 000 per QALY. Trial registration number Australian and New Zealand Clinical Trials Registry, ACTRN12615001160527. [Open Access]

VAINRE, M. , Galante, J., WATSON, P., DALGLEISH, T., HITCHCOCK, C. (2022) Protocol for the Work Engagement and Well-being Study (SWELL): A randomised controlled feasibility trial evaluating the effects of mindfulness versus light physical exercise at work, BMJ Open, 12 Apr 2022, 12(4):e050951 [Open Access]

BENNETT, M.P., KNIGHT, R., DUNNING, D., ARCHER-BOYD, A., Blakemore, S-J., DALMAIJER, E., Ford, T., Williams, J.M.G., Clegg, H., Kuyken, W., So, T., Wright, G., Lenaert, B., VAINRE, M. , WATSON, P., MYRIAD team & DALGLEISH, T. (2022) Protocol for a randomized controlled trial investigating an intervention to boost decentering in response to distressing mental experiences during adolescence: The Decentering in Adolescence Study (DECADES), BMJ Open, 30 Mar 2022, 12(3):e056864 [Open Access]

Ford, T., Esposti, M.D., Crane, C., Taylor, L., Montero-Marın, J., Blakemore, S., Bowes, L., Byford, S., DALGLEISH, T., Greenberg, M., Nuthall, E., Phillips, A., Raja, A., Ukoumunne, O.C., Viner, R.M., Williams, J.M.G., Allwood, M., Aukland, L., Casey, T., De Wilde, K., Farley, E-R., Kappelmann, N., Lord, L., Medlicott, E., Palmer, L., Petit, A., Pryor-Nitsch, I., Radley, L., Warriner, L., Sonley, A., Ahmed, S., Ball, S., Bennett, M., Dalrymple, N., DUNNING, D., Fletcher, K., Ganguli, P., Griffin, C., GRIFFITHS, K., Komninidou, K., Laws, S., Leung, J., PARKER, J., Piera Pi-Sunyer, B., Sakhardande, J.A., Shackleford, J., Tudor, K., VAINRE, M. , Wainman, B., Kuyken, W. (2021) The role of schools in early adolescents’ mental health: findings from the MYRIAD study, Journal of the American Academy of Child & Adolescent Psychiatry, 60(12):1467-1478 [Open Access]

Galante, J., Stochl, J., Dufour, G., VAINRE, M. , Wagner, A.P., Jones, P.B. (2020) Effectiveness of providing university students with a mindfulness-based intervention to increase resilience to stress: 1-year follow-up of a pragmatic randomised controlled trial, Journal of Epidemiology and Community Health,75(2):151-160 [Open Access]

Anderson, K., Howarth, E., VAINRE, M. , Humphrey, A., Jones, P.B., Ford, T.J. (2020) Advancing methodology for scoping reviews: recommendations arising from a scoping literature review (SLR) to inform transformation of Children and Adolescent Mental Health Services, BMC Medical Research Methodology, 20(1),242 [Open Access]

Burn, A-M., VAINRE, M. , Humphrey, A., Howart, E. (2020) Evaluating the CYP-IAPT transformation of child and adolescent mental health services in Cambridgeshire, UK: a qualitative implementation study., Implementation Science Communications, 1:89 [Open Access]

Turner, L., Galante, J., VAINRE, M. , Stochl,J., Dufour, G., Jones, P.B. (2020) Immune dysregulation among students exposed to exam stress and its mitigation by mindfulness training: findings from an exploratory randomised trial, Scientific Reports, 10(1): 5812 [Open Access]

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