I am a Postdoctoral Research Associate in Dr. Kate Baker’s lab, where I am currently establishing a 3D stem cell model of SYT1-associated neurodevelopmental disorder. My hope is to establish a model that will enable us to further understand the mechanistic underpinnings and pathogenicity of this synaptic vesicle cycling disorder. My work is in collaboration with colleagues at the University of Cambridge John van Geest Centre for Brain Repair and the Department of Physiology, Development and Neuroscience. This work is supported by the NIHR Cambridge Biomedical Research Centre, Great Ormond Street Hospital Charity, and the Medical Research Council.
Prior to joining the Baker lab, I completed a MPhil in Basic and Translational Neuroscience at the University of Cambridge with Dr. Andras Lakatos, where I studied cortical development using human cerebral organoids. Following this, I completed a PhD in Medical Science with Prof. Duncan Astle, using computational modelling to investigate how the socioeconomic environment, genome, and structural connectome interact to influence development.
I am an active member of the Cambridge Neuroscience Steering Committee, where I am a Representative for Equality, Diversity, Inclusion, and Well-being (EDIW).
BIGNARDI, G., DALMAIJER, E.S., ANWYL-IRVINE, A., SMITH, T. , SIUGZDAITE, R., UH, S., ASTLE, D. (2021) Longitudinal increases in childhood depression symptoms during the COVID-19 lockdown, Archives of Diseases in Childhood, 106(8), 791-797 [Open Access]
Shearer, J., Papanikolaou, N., MEISER-STEDMAN, R., McKinnon, A., DALGLEISH, T., Smith, T. , Dixon, C., Byford, S. (2017) Cost-effectiveness of cognitive therapy as an early intervention for post-traumatic stress disorder in children and adolescents: a trial based evaluation and model, Journal of Child Psychology and Psychiatry [Open Access]
WASS, S., Jones E. J.H., Gliga, T., Smith, T. J., Charman, T., Johnson, M.H. & The Basis team (2015) Shorter Spontaneous Fixation Durations in Infants with Later Emerging Autism, Nature Scientific Reports, 5:8284 [Open Access]
WASS, S., Smith, T. (2015) Visual motherese? Signal-to-noise ratios in toddler-directed television, Developmental Science, 18(1), 24-37 [Open Access]