Why do we sometimes freeze when we should act—or act when we shouldn’t? These behaviours reflect Pavlovian biases: automatic tendencies to approach rewards and avoid punishments. Though often useful, such biases can interfere with decision-making and contribute to anxiety and depression. In a preregistered, double-blind study with 800 participants, Hugo Fleming and colleagues tested whether […]
Dr Lewis Owens, CBU supporter and fundraiser, recognised in New Year’s Honours
We are delighted to send congratulations to Dr Lewis Owens on the announcement of his MBE in the New Year’s Honours List. As well as being one of the most dedicated fundraisers for the research at the CBU, Lewis has given enormously to society through his charitable works including the Rays of Sunshine charity, Prisons’ […]
Parents of children with a genetic diagnosis need better support
Advances in genetic testing have enabled families of critically ill children to receive early diagnoses that can open up new options for care and treatments. But, according to new Cambridge research published in the European Journal of Human Genetics, the medical complexity of these, often lifelong and rare conditions, can lead to parental anxiety and distress, […]
Annalise Whines runner-up at MRC Max Perutz Science Communication Awards
Many congratulations to MRC CBU’s PhD student Annalise Whines, who won the runner-up prize at the MRC Max Perutz Science Communication Awards in the video category. Annalise’s video was titled ‘Does motivation change across the menstrual cycle?’ Annalise said: “I’m thrilled to have been awarded the runner-up prize and to be able to publicly share […]
Scientists identify five ages of the human brain over a lifetime
A study led by Cambridge’s MRC Cognition and Brain Sciences Unit have identified five “major epochs” of brain structure over the course of a human life, as our brains rewire to support different ways of thinking while we grow, mature, and ultimately decline. The team compared the brains of 3,802 people between zero and ninety […]
Paying attention to John Duncan
Throughout his distinguished career, based predominantly at the MRC Cognition and Brain Sciences Unit (MRC CBU), John Duncan has made numerous influential contributions to understanding the behavioural and brain basis of attention and intelligence. John’s ideas, invariably combining theoretical eloquence, experimental rigour, and convergent methodology, have had huge impact across domains of experimental psychology, neuropsychology, […]
COGNESTIC 2026
The MRC Cognition and Brain Sciences Unit (MRC CBU) is excited to announce that COGNESTIC 2026 will take place in Cambridge from 14–25 September 2026. This two-week summer school brings together early-career researchers, advanced trainees, and established scientists for an intensive programme focused on state-of-the-art methods in open neuroimaging analysis. What to Expect: Hands-on Training […]
Multidimensional cognitive deficits in the typical and atypical variants of Alzheimer’s disease
New research by Henderson and colleagues found graded distinctions among typical amnestic and atypical (language, visual) Alzheimer’s phenotypes. The findings support a transdiagnostic, multidimensional model of AD that spans all subtypes. Read the full paper here: Henderson, S.K., Murley, A.G., Cope, T.E. et al. Multidimensional cognitive deficits in the typical and atypical variants of Alzheimer’s disease. Alz Res […]
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MRC Cognition and Brain Sciences Unit

