Around 1% of people around the world have an intellectual disability (ID), otherwise known as a learning disability. While these disabilities can impact many aspects of life, we are only beginning to understand their genetic causes due to recent advancements in gene sequencing methods. These technologies have allowed researchers to also look at how specific […]

Although most of us experience early education in a typical classroom setting, we all learn differently. For those with neurodevelopmental conditions like ADHD, dyslexia, and autism, it can be particularly hard to pick up new skills and knowledge in a classroom. In this study, researchers at the MRC CBU looked at how variations in children’s […]

In 2015, Kate Baker and colleagues published the first report of a child with severe disability and a mutation in Synaptotagmin 1 (SYT1).  SYT1 is the critical molecular trigger for fast, synchronous neurotransmitter release, highlighting an important new mechanism for developmental disorders.  Following this first case report, genomic testing laboratories around the world began to […]