Recent research from the Cambridge Centre for Ageing and Neuroscience (CamCAN; www.cam-can.org) shows that, when pulse pressure – the difference between systolic and diastolic blood pressure – gets too high, it can damage the brain’s “wiring” (white matter), making it harder to think fast and solve puzzles. Treating blood pressure may therefore help maintain cognitive […]
Researchers set out how to combine brain stimulation with neuroimaging for powerful inference about brain function
MRC CBU researchers joined with experts from across the world to produce a consensus on and functional guide to the challenging but powerful combination of brain stimulation with neuroimaging using concurrent TMS-fMRI. Abstract Concurrent transcranial magnetic stimulation (TMS) and functional magnetic resonance imaging (TMS-fMRI) provides a step-change in the toolkit of neuroscience research. TMS enables […]
Ten patient-led priorities for interoception research in psychiatry
How do people with mental health conditions experience bodily signals? Lydia Hickman and Gabriel Mackie’s new paper in eClinicalMedicine explores lived experiences and patient priorities for interoception research. Individuals with psychiatric disorders report differences in bodily experiences. However, formal priority setting by people with lived experience of mental health conditions has so far been overlooked […]
MRC CBU Science Night – Cambridge Festival 2025
Inside the Mind: Exploring the Human Brain Date: Wednesday 19 March 2025 Time: 6pm – 8.30pm Location: MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge, CB2 7EF Directions to the Unit: http://www.mrc-cbu.cam.ac.uk/contact-us/ https://www.mrc-cbu.cam.ac.uk/events/science-night/ As part of the Cambridge Festival 2025, the MRC Cognition and Brain Sciences Unit are hosting a fun filled and […]
Behavioural changes in frontotemporal dementia: neuropsychological and neuroanatomical correlates
A new study by Rouse and colleagues at the MRC Cognition and Brain Sciences Unit, addressed two important clinical questions in frontotemporal dementia (FTD); (a) are there qualitative or clear distinctions between behavioural profiles in behavioural-variant FTD and semantic dementia, and (b) what are the precise roles of the prefrontal cortex and anterior temporal lobes […]
Dr Orben leads governmental project to understand impact of smartphones and social media on young people
Cambridge researchers are leading the first phase of a new research project that will lay the groundwork for future studies into the impact on children of smartphone and social media use. The work has been commissioned by the UK government’s Department for Science, Innovation and Technology after a review by the UK Chief Medical Officer […]
Differences in brain connectivity in premature infants are related to altered wiring constraints of structural brain networks
The way the brain organizes in utero is associated with cognition and behaviour in later life. Infants that are born early have differently organized brain networks compared to infants born at term. Our study used data from the developing Human Connectome Project to explore structural topology across neonates born at different gestational ages. Our results […]
Matt Rouse awarded 2024 Milo Keynes Thesis Prize
Congratulation to Matt Rouse from the MRC Cognition and Brain Science Unit (MRC CBU), who has been awarded the 2024 Milo Keynes Prize by the University of Cambridge School of Clinical Medicine, for the outstanding quality of his PhD thesis. Matt’s thesis is titled “Social-semantic knowledge and behavioural changes in frontotemporal dementia”. Matt said: “I am delighted […]
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MRC Cognition and Brain Sciences Unit

