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Prospective memory in multiple sclerosis
Foley, J., WILSON, B. & Shiel, A.
Brain Impairment, 5(1), p. 99, 2004
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Examples of prospective memory include remembering to make a phone call at a certain time or to take medication in the morning. Prospective memory, or 'realising delayed intentions' is one of the most commonly used types of memory and its impairment significantly disabling. Several authors have found evidence to suggest that this type of memory is impaired in individuals with Multiple Sclerosis (MS). These studies used individualised assessment measures specific to their studies, however, rather than using standardised methodology. Using the newly developed Cambridge Prospective Memory Test (CAMPROMPT) and other tests of neuropsychological and psychosocial functioning, participants with MS, as compared to healthy controls, were shown to have comparative deficits in prospective memory. These were significantly correlated with some other neuropsychological measures, including those assessing memory. Performance on the CAMPROMPT was also significantly correlated with Barthel Index, EDSS and disease course suggesting that prospective memory is mediated by MS disease type, impairment and resulting disability. No significant relationship was found to exist with the attentional and executive functioning measures. However, this may have been due to the very low number of individuals who were able to participate on these tests. As expected, performance was not found to be statistically significantly correlated to fatigue, locus of control, anxiety or depression. The results indicate that the CAMPROMPT is a sensitive measure of prospective memory in MS.