I am an Investigator Scientist on the Cognition, Emotion, and Mental Health Programme. My research investigates the brain basis of neuropsychiatric disorders: what changes in our brain during periods of mental ill-health? How does the way our brains process the world make us more or less susceptible to developing a mental health disorder? And finally, how can we capitalise on the tools of neuroscience - brain imaging, brain stimulation, computational modelling - to improve our ability to treat mental health disorders?
To answer these questions, I conduct three types of experiments:
- Basic neuroscience experiments investigating how we make decisions, process rewards and emotions, and other cognitive mechanisms important for maintaining mental health (e.g., this MR imaging study in adolescents, or this behavioural study)
- Clinical experiments in patient populations, such as people suffering from major depressive disorder, to investigate brain and behavioural differences that occur as a result of a mental health condition (e.g., this fMRI study, or this behavioural study)
- Translational/intervention studies testing out new ways of treating mental health disorders (such as this trial of a new treatment for depression or this experimental study of a new type of brain stimulation)
- Nord CL, Halahakoon DC, Limbachya T, Charpentier CJ, Lally N, Liebowitz J, Pilling S, Roiser JP. Neural predictors of treatment response to brain stimulation and psychological therapy in depression: a double-blind randomized controlled trial. Neuropsychopharmacology, In Press. doi: 10.1038/s41386-019-0401-0
- Nord CL, Gray A, Robinson OJ, Roiser JP. Reliability of prefrontal-amygdala coupling during emotional face processing. Brain Sciences (2019), 9(4), 89. doi:10.3390/brainsci9040089
- Nord CL, Kim S, Rømer Thomsen,K, Callesen MB, Kvamme TL, Jensen M, Pedersen MU, Voon V. The myeloarchictecture of impulsivity: premature responding in youth is associated with decreased myelination of ventral putamen. Neuropsychopharmacology (2019) 0:1–8. doi: 10.1038/s41386-019-0343-6.
- Nord CL, Popa T, Smith E, Hannah R, Doñamayor N, Weidacker K, Bays PM, Rothwell J, Voon. The effect of frontoparietal paired associative stimulation on decision-making and working memory. Cortex (2019) 117: 266-276. doi:10.1016/j.cortex.2019.03.015
- Kohl S, Hannah R, Rocchi L, Nord CL, Rothwell J, Voon V. Cortical paired associative stimulation influences response inhibition: cortico-cortical and cortico-subcortical networks. Biological Psychiatry (2019) 85:355-363. doi: 10.1016/j.biopsych.2018.03.009.
- Nord CL, Lawson RP, Huys QJM, Roiser JP. Exaggerated loss-specific Pavlovian-instrumental transfer in unmedicated major depression. Scientific Reports (2018) 8:12582 doi: 10.1038/s41598-018-30828-5.
- Nord CL, Valton V, Wood JX, Roiser JP. Power up: a re-analysis of ‘power failures’ in neuroscience using mixture modelling. Journal of Neuroscience (2017) 3592-16. doi:10.1523/JNEUROSCI.3592-16.2017.
- Nord CL, Gray A, Charpentier CJ, Robinson OJ, Roiser JP. Unreliability of putative fMRI biomarkers during emotional face processing. NeuroImage (2017) 156:119-127.
- Nord CL, Forster S, Halahakoon C, Munafò, MM Roiser, JP. Prefrontal cortex stimulation does not affect emotional bias, but may slow emotion identification. Social Cognitive and Affective Neuroscience (2017) 12(5): 839-847.
- Nord CL, Prabhu G, Nolte T, Fonagy P, Dolan RJ, Moutoussis M. Vigour in active avoidance. Scientific Reports (2017) 7(60). doi:10.1038/s41598-017-00127-6.
- Lawson RP, Nord CL, Seymour B, Thomas DL, Dayan P, Pilling S, Roiser JP. Disrupted habenula function in major depression. Molecular Psychiatry (2017) 22(2):202-208. doi: 10.1038/mp.2016.81
- Torrisi S, Nord CL, Balderston N, Roiser JP, Grillon C, Ernst M. Resting state connectivity of the human habenula at ultra-high field. Neuroimage (2016) 147:872-879. doi: 10.1016/j.neuroimage.2016.10.034
- Nord CL, Roiser JP. Non-invasive direct current brain stimulation for depression: the evidence behind the hype. Advances in Clinical Neurology and Rehabilitation (2015) 15(5):9-11.
- Nord CL, Lally N, Charpentier C. Harnessing electric potential: DLPFC tDCS induces widespread brain perfusion changes. Frontiers in Systems Neuroscience (2013) 7:99. doi: 10.3389/fnsys.2013.00099
- Lally N, Nord CL, Walsh V, Roiser J. Does excitatory fronto-extracerebral tDCS lead to improved working memory performance? F1000 Research (2013) 2:219. doi: 10.12688/f1000research.2-219.v2