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Selective tuning of the BOLD response during simple target detection dissociates human frontoparietal sub-regions
Authors:
HAMPSHIRE, A., DUNCAN, J. & OWEN, A.M.
Reference:
Journal of Neuroscience, 27(23), 6219-6223.
Year of publication:
2007
CBU number:
6482
Abstract:
Current models of working memory and focal attention converge upon the idea of an adaptable global system, distributed across a network of frontal and parietal brain regions. Here we examine how the human frontoparietal network selectively adapts to represent currently relevant information during a simple attentional task - monitoring for a target item in a series of non-targets. Across the whole frontoparietal network there is selective response to targets, in line with a global system for coding task-relevant inputs. At the same time, there are striking dissociations in response to non-targets; while ventrolateral frontal cortex responds just to the target, more dorsal/ anterior regions respond to all stimuli from the target category. The results show different degrees of target selectivity across different regions of the frontoparietal network. Title might also be listed as: Selective tuning of the blood oxygenation level-dependent response during simple target detection dissociates human frontoparietal subregions.