We want to understanding brain systems in childhood, how they function, how they are organised, and their role in children’s developing cognitive skills. In particular we are also interested in children who struggle, find school difficult or fail to thrive. To do this we develop new ways to study the brain in childhood, using non-invasive imaging technique like MRI and magnetoencephalography (MEG). These innovations in neuroscience are then integrated with lots of different sources of information, including: genetics, different aspects of cognition (e.g. attention and memory), educational attainment (e.g. reading and maths data), detailed accounts of behaviour and mental health.
Our aim is to understand the mechanisms of brain development and the factors that can influence it. Combining rich datasets with innovations in analysis we want to identify concurrent and longitudinal predictors of emerging and persistent cognitive, learning and mental health problems, and pinpoint risk and resilience factors that will inform future targets for intervention.
This programme is led by Duncan Astle
Team members: Jonathan Jones (postdoc), Edwin Dalmaijer (postdoc), Roma Siugzdaite (postdoc), Elise Ng-Cordell (Research Assistant), Mengya Zhang (PhD student), Joe Rennie (PhD student), Alex Irvine (PhD student), Giacomo Bignardi (PhD student), Tess. Liddell (PhD student), Stepheni Uh (PhD student)
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Astle, D. E., Bathelt, J., CALM Team, & Holmes, J. (2019). Remapping the cognitive and neural profiles of children who struggle at school. Developmental science, 22(1), e12747.
Bathelt, J., Scerif, G., Nobre, K., & Astle, D. E. (2019). Whole-brain white matter organization, intelligence, and educational attainment. Trends in Neuroscience and Education.
Bathelt, J., Johnson, A., Zhang, M., & Astle, D. E. (2019). The cingulum as a marker of individual differences in neurocognitive development. Nature: Scientific reports, 9(1), 2281.
Bathelt, J., Gathercole, S. E., Butterfield, S., CALM team, & Astle, D. E. (2018). Children’s academic attainment is linked to the global organization of the white matter connectome. Developmental Science, e12662.
Bathelt, J., Holmes, J., The CALM Team, & Astle, D. E., (2018). Data-Driven Subtyping of Executive Function–Related Behavioral Problems in Children. Journal of the American Academy of Child & Adolescent Psychiatry, 57(4), 252-262.
Bathelt, J., Gathercole, S. E., Johnson, A., & Astle, D. E. (2018). Differences in brain morphology and working memory capacity across childhood. Developmental science, 21(3), e12579.